Plants vs Brainrots Mutation Machine Guide

The Mutation Machine in Plants vs Brainrots has completely changed how players upgrade their plants and brainrots. It allows you to merge mutated variants to create stronger forms and earn valuable rewards — from premium items and potions to exclusive seeds and mythical brainrots.

If you’ve been exploring the latest Merge Madness update, here’s a complete breakdown of how the mutation machine works, all available rewards, and the best way to use it effectively.


What Is the Mutation Machine?

The Mutation Machine is a special fusion system that lets you mutate plants or brainrots by combining two versions of the same unit with different mutation levels. Doing this not only produces a stronger variant but also grants extra rewards such as money, potions, and rare seeds.

You can find the Mutation Machine at the center island, accessible through the mirror portal near your base.


How To Use the Mutation Machine in Plants vs Brainrots Roblox

  1. Go to the Center Island
    Use the mirror portal at your base to reach the Mutation Machine area.

  2. Select Two Mutated Units
    Hold two of the same plant or brainrot species – but with different mutations. (Example: Frozen variant + Neon variant).

  3. Interact with the Machine
    Approach the machine and press E to place both units inside.

  4. Power It Up
    Next to the Mutation Machine, you’ll find an EXP station. Use any EXP items such as vials or potions to power the machine and begin the process.

  5. Wait for Completion
    The mutation timer depends on the rarity of the brainrot or plant. Legendary and God-tier units take longer than common ones.

  6. Claim Your Rewards
    Once the process ends, your new mutated variant and reward will automatically appear in your inventory.


Plants vs Brainrots Mutation Machine Rewards List

The Mutation Machine gives unique rewards based on your merge count. Each successful merge unlocks progressively better items.

Mutation Merge Counter Rewards
Mutation Merge #1 Money
Mutation Merge #2 Money + Premium Water Bucket
Mutation Merge #3 Frost Grenade + Orcalelo Orcala
Mutation Merge #4 Money
Mutation Merge #5 Base Card Pack + Premium Water Bucket + Sunflower Seed
Mutation Merge #6 Witch Potion
Mutation Merge #7 Money + Gangster Footera
Mutation Merge #8 Money + Sunflower Seed
Mutation Merge #9 Money + Dragon Fruit Seed + Bandito Bobrito
Mutation Merge #10 Money
Mutation Merge #11 Frost Grenade + Orcalelo Orcala
Mutation Merge #12–#25 TBA

(More rewards will be revealed in future updates.)


Mutation Mania Event

If you want to speed up your mutation process, watch for the Mutation Mania weather event.

During this event:

  • The Mutation Machine, Merge Machine, and Plant Extractor all run at 2x speed.

  • The event lasts 10 minutes every hour, giving players the best window to perform merges efficiently.

This is easily the best time to combine higher-tier brainrots since the process completes twice as fast.


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Pro Tips

  • Always merge same-type variants: Combining different species won’t work.

  • Save EXP items: You’ll need vials or potions to activate the mutation machine.

  • Track your merges: Each merge number unlocks better items — aim for #5 and #9 merges for top rewards.

  • Use Mutation Mania windows: Double-speed periods save tons of time.


Final Thoughts

The Mutation Machine in Plants vs Brainrots isn’t just about creating stronger variants – it’s a rewarding system that ties progression and resource management together. Between money bonuses, rare items, and exclusive seeds, every merge brings you closer to maxing out your team.

With Mutation Mania running hourly, it’s the perfect time to jump in and start merging. Who knows? Your next fusion might unlock a brand-new Secret brainrot.